Description

2-Azabicyclo[2.2.2]octane is a versatile and structurally significant bicyclic tertiary amine, serving as a crucial building block in advanced organic synthesis. Its rigid, three-dimensional scaffold is highly valued for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of drug candidates, especially those targeting the central nervous system (CNS).
• Ligand and Catalyst Precursor: Used in the development of nitrogen-containing ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, and plant growth regulators with enhanced activity.
• Material Science: Acts as a monomer or cross-linking agent in the production of specialty polymers and resins.
• Chemical Biology Probe: Utilized to create molecular probes for studying enzyme mechanisms and biological pathways.
• Academic & R&D: A fundamental reagent in university and industrial research laboratories for methodological development and discovery chemistry.

Basic Information

Product Name	2-Azabicyclo[2.2.2]octane
CAS No.	280-38-6
Molecular Formula	C7H13N
Molecular Weight	111.18 g/mol
Synonyms	2-Azabicyclo[2.2.2]octane; Quinuclidine; 1-Azabicyclo[2.2.2]octane (common misnomer); 1-Azanorbornane; Bicyclo[2.2.2]octan-2-amine; ABCO; NSC 106977; EINECS 205-999-9
EINECS	205-999-9

Quality Control

Our 2-Azabicyclo[2.2.2]octane is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and oxidizing agents. For long-term storage under an inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Melting Point	156 - 160 °C
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.