Description

Bicyclo[2.2.2]Octane CAS NO 280-33-1 is a highly symmetrical, rigid, and saturated hydrocarbon cage compound, serving as a fundamental and versatile building block in advanced organic synthesis and materials science. Its unique three-dimensional structure provides exceptional steric and electronic properties, making it invaluable for creating complex molecular architectures with precise control. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries, where it is used to develop novel active ingredients, ligands, and high-performance materials.

Application

• Pharmaceutical Intermediate: A key rigid scaffold for the synthesis of novel drug candidates, particularly in neurology and oncology, where its structure can influence bioavailability and receptor binding.
• Agrochemical Research: Used as a core structure in the development of new pesticides and herbicides, providing stability and specific activity.
• Ligand & Catalyst Design: Serves as a backbone for constructing sophisticated chelating ligands and organometallic catalysts used in asymmetric synthesis and polymerization.
• Materials Science: Incorporated into specialty polymers, dendrimers, and metal-organic frameworks (MOFs) to enhance thermal stability, rigidity, and porosity.
• Academic & Industrial R&D: A fundamental reagent for methodological studies in organic chemistry, including strain-release reactions and the study of non-classical bonding.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing unique musk-like or woody odorants due to its stable, compact hydrocarbon framework.

Basic Information

Item	Details
Product Name	Bicyclo[2.2.2]Octane
CAS No.	280-33-1
Molecular Formula	C8H12
Molecular Weight	108.18 g/mol
Synonyms	Bicyclo[2.2.2]octane; 1,4-Ethanobicyclo[2.2.2]octane; Octahydro-1,4:5,8-dimethanonaphthalene; Triethylenediamine hydrocarbon analog; [2.2.2]Bicyclooctane; 2,2,2-Bicyclooctane; BCO (abbreviation); ENT 25,296
EINECS	205-995-2

Quality Control

Our Bicyclo[2.2.2]Octane is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles where applicable, ensuring reliability for your most demanding R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Melting Point	165 - 170 °C
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.