Description

8-Oxa-3-Azabicyclo[3.2.1]Octane is a versatile bicyclic organic compound featuring both ether and amine functionalities within a constrained ring system. This unique structure makes it a valuable building block and intermediate in advanced organic synthesis, particularly for the development of complex molecules with specific three-dimensional architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the construction of nitrogen- and oxygen-containing heterocycles found in drug candidates, such as alkaloid analogs and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require rigid, bicyclic scaffolds for optimal biological activity.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands in asymmetric catalysis and metal-organic frameworks (MOFs) due to its dual heteroatom donor sites.
• Material Science Research: Investigated as a monomer or cross-linking agent for producing specialty polymers with enhanced thermal stability or specific chemical functionalities.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including ring-opening reactions and scaffold diversification.

Basic Information

Product Name	8-Oxa-3-Azabicyclo[3.2.1]Octane
CAS No.	280-13-7
Molecular Formula	C₆H₁₁NO
Molecular Weight	113.16 g/mol
Synonyms	3-Aza-8-oxabicyclo[3.2.1]octane; 8-Oxa-3-azabicyclo[3.2.1]octane; Tropane, 8-oxa-3-aza-; 8-Oxa-3-azatricyclo[3.2.1.0³,⁷]octane; 3-Azatropane, 8-oxa-; NSC 106977; 8-Oxatropan-3-amine (tautomeric form)
EINECS	Contact for details

Quality Control

Our 8-Oxa-3-Azabicyclo[3.2.1]Octane is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatography and spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results are provided with every shipment. We can support development projects requiring material that meets research-grade or higher specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥95% (Research Grade)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.