Description

1-Azabicyclo[2.2.1]heptane is a versatile and structurally significant bicyclic amine, widely recognized as a key building block in organic synthesis. Its rigid, bridged framework makes it an invaluable scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for chemists and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for neurological and cardiovascular drugs.
• Ligand and Catalyst Synthesis: Used to create chiral ligands and organocatalysts for asymmetric synthesis, enabling the production of enantiomerically pure compounds.
• Agrochemical Research: Serves as a core structure for developing novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Incorporated into polymers and advanced materials to modify thermal stability, rigidity, and chemical resistance.
• Chemical Biology Probe: Utilized in medicinal chemistry to design molecular probes for studying enzyme mechanisms and biological pathways.
• Fine Chemical Synthesis: Acts as a building block for complex natural product analogs and specialty chemicals.

Basic Information

Product Name	1-Azabicyclo[2.2.1]heptane
CAS No.	279-27-6
Molecular Formula	C6H11N
Molecular Weight	97.16 g/mol
Synonyms	1-Azanorbornane; 2,5-Methano-2H-pyrrole, tetrahydro-; Nortropidine; 1-Azabicyclo[2.2.1]heptane; Bicyclo[2.2.1]heptane, 1-aza-; 1-Azabicyclo[2.2.1]heptane; Tropan-8-ol, 3-benzoyloxy-8-methyl-, endo-; 1-Azabicyclo[2.2.1]heptane hydrochloride
EINECS	205-994-6

Quality Control

Our 1-Azabicyclo[2.2.1]heptane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chromatography and spectroscopic methods, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product quality. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.