Description

Methyl 3-Amino-5,6-Dihydro-4H-Thieno[2,3-C]Pyrrole-2-Carboxylate Dihydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure, making it a critical building block for modern drug discovery. This compound is essential for medicinal chemistry research and development, particularly in the synthesis of novel small molecule therapeutics targeting a range of diseases. It is primarily sought after by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in developing innovative active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Active Pharmaceutical Ingredient (API) Development: Used in the development and scale-up processes for new chemical entities (NCEs) requiring a fused thienopyrrole core.
• Bioconjugation & Probe Synthesis: The amino group allows for functionalization, making it suitable for creating labeled compounds for biological testing and diagnostic probes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical clients with custom synthesis and process development.

Basic Information

Product Name	Methyl 3-Amino-5,6-Dihydro-4H-Thieno[2,3-C]Pyrrole-2-Carboxylate Dihydrochloride
CAS No.	1998216-51-5
Molecular Formula	C8H12Cl2N2O2S
Molecular Weight	271.16 g/mol
Synonyms	Methyl 3-amino-4,7-dihydro-5H-thieno[2,3-c]pyrrole-2-carboxylate dihydrochloride; 3-Amino-5,6-dihydro-4H-thieno[2,3-c]pyrrole-2-carboxylic acid methyl ester dihydrochloride; 2-Carbomethoxy-3-amino-4,7-dihydro-5H-thieno[2,3-c]pyrrole dihydrochloride; Thienopyrrole-2-carboxylate intermediate; 1998216-51-5; Methyl 3-amino-4,7-dihydrothieno[2,3-c]pyrrole-2-carboxylate HCl salt
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Amino-5,6-Dihydro-4H-Thieno[2,3-C]Pyrrole-2-Carboxylate Dihydrochloride adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.