Description

2-Doramectin CAS NO 1987882-63-2 is a high-purity chemical compound belonging to the macrocyclic lactone class, specifically a derivative of doramectin. This compound is critical for research and development in the pharmaceutical and veterinary medicine sectors, where precise molecular structure and purity are paramount. It serves as a key intermediate or reference standard for scientists developing novel antiparasitic agents and conducting advanced pharmacological studies.

Application

• Primary use as a reference standard in analytical chemistry for method development and validation.
• Critical pharmaceutical intermediate in the synthesis of next-generation antiparasitic drugs.
• Active ingredient research for veterinary applications targeting endo- and ectoparasites.
• Biochemical research tool for studying GABA-gated chloride channels and parasite neurophysiology.
• Raw material in the development of long-acting formulations and injectable solutions.
• Use in stability studies and impurity profiling for regulatory submissions.

Basic Information

Product Name	2-Doramectin
CAS No.	1987882-63-2
Molecular Formula	C₅₀H₇₄O₁₄
Molecular Weight	899.1 g/mol
Synonyms	25-Cyclohexyl-5-O-demethyl-25-de(1-methylpropyl)avermectin A1a; Doramectin Derivative; 2-Deoxy-2-Doramectin; (10E,14E,16E)-(1R,4S,5'S,6R,6'R,8R,12S,13S,20R,21R,24S)-6'-[(S)-sec-butyl]-21,24-dihydroxy-5',11,13,22-tetramethyl-2-oxo-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6-spiro-2'-(5',6'-dihydro-2'H-pyran)-12-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-3-O-methyl-α-L-arabino-hexopyranoside
EINECS	Contact for details

Quality Control

Our 2-Doramectin is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.