Description

3-Amino-6-Methoxy-1H-Indole-2-Carbohydrazide Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1986331-05-8. This compound is a critical building block in the synthesis of complex heterocyclic molecules, offering a versatile scaffold for medicinal chemistry research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery and production of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and oncological pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Organic Synthesis Building Block: Used in the construction of complex indole-based heterocycles, including fused ring systems and functionalized derivatives.
• Biochemical Research: Potential use as a reagent or probe in biochemical assays and enzyme inhibition studies due to its reactive hydrazide and amino functional groups.
• Agrochemical Development: May be investigated as an intermediate for novel crop protection agents and pesticides.
• Material Science: Exploration of its use in the synthesis of specialty polymers or organic electronic materials.

Basic Information

Product Name	3-Amino-6-Methoxy-1H-Indole-2-Carbohydrazide Hydrochloride
CAS No.	1986331-05-8
Molecular Formula	C10H13N5O2 • HCl
Molecular Weight	271.70 g/mol (Free base: 235.24 g/mol)
Synonyms	3-Amino-6-methoxy-1H-indole-2-carbohydrazide HCl; 6-Methoxy-3-aminoindole-2-carbohydrazide hydrochloride; 1H-Indole-2-carbohydrazide, 3-amino-6-methoxy-, hydrochloride; 2-Hydrazinylcarbonyl-6-methoxy-1H-indol-3-amine hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Amino-6-Methoxy-1H-Indole-2-Carbohydrazide Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a Certificate of Analysis (COA) with every shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.