Description

1-(3-Thienyl)-1H-Pyrazole-4-Boronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic chemistry. Its value lies in its role as a key reagent in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it is used to develop new active ingredients and advanced functional molecules.

Application

• Pharmaceutical Intermediate: A crucial synthon for constructing novel drug candidates, particularly in kinase inhibitor and CNS-active compound research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Material Science Research: Serves as a monomer or precursor for creating conjugated polymers and organic electronic materials (OLEDs, OFETs).
• Chemical Biology & Probe Development: Employed in synthesizing molecular probes and bioconjugates for target identification and validation.
• Catalyst Ligand Synthesis: Acts as a precursor for synthesizing specialized ligands used in homogeneous catalysis.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis services and scale-up production under cGMP conditions.

Basic Information

Product Name	1-(3-Thienyl)-1H-Pyrazole-4-Boronic Acid
CAS No.	1974329-41-3
Molecular Formula	C7H7BN2O2S
Molecular Weight	194.02 g/mol
Synonyms	1-(Thiophen-3-yl)-1H-pyrazole-4-boronic acid; [1-(3-Thienyl)-1H-pyrazol-4-yl]boronic acid; 1-(Thien-3-yl)-1H-pyrazole-4-boronic acid; 1-(3-Thienyl)-1H-pyrazole-4-boronic acid pinacol ester (common derivative); 3-(4-Boronopyrazol-1-yl)thiophene; 1H-Pyrazole-4-boronic acid, 1-(3-thienyl)-; B-[1-(3-Thienyl)-1H-pyrazol-4-yl]boronic acid
EINECS	Contact for details

Quality Control

Our 1-(3-Thienyl)-1H-Pyrazole-4-Boronic Acid is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. Comprehensive Certificates of Analysis (COA) with detailed chromatographic data are provided with each shipment. We support development under quality frameworks including ISO 9001 and can supply material suitable for use in cGMP environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) when possible to maintain stability and purity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.