Description

Methanone, [2-(Ethylsulfonyl)Phenyl][(2S)-4-(6-Fluoro-2-Benzothiazolyl)-2-Methyl-1-Piperazinyl]- is a sophisticated, high-purity organic compound designed for advanced research and development applications. This molecule is of significant interest due to its complex heterocyclic structure, which incorporates a benzothiazole core and a piperazine ring, making it a valuable intermediate in pharmaceutical discovery. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for the synthesis of novel active pharmaceutical ingredients (APIs) and as a key building block in medicinal chemistry programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its unique fluorinated benzothiazole-piperazine scaffold.
• Active Pharmaceutical Ingredient (API) Development: Employed as a precursor in the development and scale-up of new therapeutic agents.
• Biochemical Research: Acts as a tool compound or a ligand in biochemical assays and pharmacological studies.
• Process Chemistry: Utilized in route scouting and process optimization for the efficient and scalable manufacture of complex molecules.

Basic Information

Product Name	Methanone, [2-(Ethylsulfonyl)Phenyl][(2S)-4-(6-Fluoro-2-Benzothiazolyl)-2-Methyl-1-Piperazinyl]-
CAS No.	1971937-18-4
Molecular Formula	C21H22FN3O3S2
Molecular Weight	447.55 g/mol
Synonyms	(2S)-4-(6-Fluoro-1,3-benzothiazol-2-yl)-2-methyl-1-[(2-ethylsulfonyl)phenyl]methanone-1-piperazine; 1-[(2-Ethylsulfonyl)phenyl]-[(2S)-4-(6-fluoro-2-benzothiazolyl)-2-methyl-1-piperazinyl]methanone; (S)-1-(2-(Ethylsulfonyl)phenyl)-4-(6-fluorobenzo[d]thiazol-2-yl)-2-methylpiperazin-1-yl)methanone; 1971937-18-4; Fluorinated Benzothiazole-Piperazine Ketone; Sulfone-Piperazine-Benzothiazole Building Block.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Each batch undergoes comprehensive analytical characterization using techniques including HPLC, NMR, and LC-MS to confirm identity and ensure high purity. Certificates of Analysis (COA) detailing purity, impurity profile, and other critical parameters are provided with every shipment. We support development projects with custom synthesis and scale-up services, ensuring consistent quality from milligram to kilogram quantities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.