Description

[5-(Trifluoromethyl)Thiophen-2-Yl]Methanamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate and building block. This compound is valued for its unique trifluoromethyl-thiophene scaffold, which is critical for modulating the physicochemical and pharmacokinetic properties of active pharmaceutical ingredients. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science industries for the development of novel small-molecule therapeutics and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the synthesis of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a labeled compound in biochemical assays.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis services catering to the fine chemical and life science sectors.

Basic Information

Product Name	[5-(Trifluoromethyl)Thiophen-2-Yl]Methanamine Hydrochloride
CAS No.	1971858-34-0
Molecular Formula	C6H7ClF3NS
Molecular Weight	217.64 g/mol
Synonyms	1-[5-(Trifluoromethyl)thiophen-2-yl]methanamine hydrochloride; (5-(Trifluoromethyl)thiophen-2-yl)methanamine HCl; 2-(Aminomethyl)-5-(trifluoromethyl)thiophene hydrochloride; 5-(Trifluoromethyl)-2-thiophenemethylamine hydrochloride; α-Amino-5-(trifluoromethyl)-2-thiophenemethane hydrochloride
EINECS	Contact for details

Quality Control

Our [5-(Trifluoromethyl)Thiophen-2-Yl]Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.