Description

Ethyl 6-Methoxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylate Hydrochloride is a high-purity, synthetically derived organic salt of significant interest in advanced chemical synthesis. This compound matters as a critical pharmaceutical intermediate and building block for research into bioactive molecules, particularly those targeting neurological pathways. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of new active ingredients.

Application

• Key Intermediate in Pharmaceutical Synthesis: Serves as a crucial precursor in the multi-step synthesis of complex drug candidates, particularly those with tetrahydroisoquinoline scaffolds.
• Building Block for Neurological Research: Used in medicinal chemistry programs focused on developing compounds for central nervous system (CNS) disorders.
• Agrochemical Intermediate: Employed in the research and development of novel pesticides and herbicides, leveraging its heterocyclic structure.
• Fine Chemical Production: Acts as a specialized intermediate for synthesizing dyes, pigments, and other performance chemicals.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for methodological studies and novel compound library generation.
• Process Chemistry & Scale-Up: Suitable for optimization from milligram to kilogram scale, supporting route development for commercial manufacturing.

Basic Information

Product Name	Ethyl 6-Methoxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylate Hydrochloride
CAS No.	1965308-78-4
Molecular Formula	C₁₃H₁₇NO₃·HCl
Molecular Weight	271.74 g/mol (Free base: 235.28 g/mol)
Synonyms	6-Methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid ethyl ester hydrochloride; Ethyl 6-methoxy-3,4-dihydro-1H-isoquinoline-1-carboxylate hydrochloride; 1-Carbethoxy-6-methoxy-1,2,3,4-tetrahydroisoquinoline hydrochloride; 6-Methoxy-1,2,3,4-tetrahydro-1-isoquinolinecarboxylic Acid Ethyl Ester Hydrochloride; ETIQ derivative; CAS 1965308-78-4
EINECS	Contact for details

Quality Control

Our Ethyl 6-Methoxy-1,2,3,4-Tetrahydro-Isoquinoline-1-Carboxylate Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request. We support development and commercial projects requiring material that meets exacting GMP-grade or research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.