Description

4-Chloroisoquinolin-5-Ol is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents and agrochemicals, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its chlorinated isoquinoline scaffold.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a building block for electron-transport or host materials in the fabrication of advanced display technologies.
• Ligand Synthesis for Catalysis: Employed in the preparation of novel nitrogen-containing ligands for transition metal catalysts used in cross-coupling and other organic transformations.
• Fluorescent Probe Development: Utilized as a core structure for creating sensitive chemical sensors and bio-imaging agents due to its inherent photophysical properties.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new chemical spaces in both university laboratories and corporate research centers.

Basic Information

Product Name	4-Chloroisoquinolin-5-Ol
CAS No.	1956384-89-6
Molecular Formula	C9H6ClNO
Molecular Weight	179.60 g/mol
Synonyms	5-Hydroxy-4-chloroisoquinoline; 4-Chloro-5-hydroxyisoquinoline; 4-Chloroisoquinolin-5-ol; 4-Chloro-5-isoquinolinol; 1956384-89-6; 4-Chloro-5-isoquinolin-5-ol; 4-Chloro-5-isoquinolinol; 4-Cl-5-OH-isoquinoline
EINECS	Contact for details

Quality Control

Our 4-Chloroisoquinolin-5-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.