Description

Ethyl 3-Bromo-1H-Pyrrolo[3,2-B]Pyridine-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS number 1956378-91-8. This compound is a critical building block in modern medicinal chemistry, valued for its fused heterocyclic structure which serves as a versatile scaffold for drug discovery. It is primarily sought after by research institutions and pharmaceutical companies engaged in the synthesis of novel small-molecule therapeutics, particularly in oncology and CNS research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce the pyrrolopyridine moiety into more complex molecular architectures.
• Agrochemical Research: Potential intermediate in the development of new active ingredients for crop protection.
• Material Science: Investigated as a precursor for organic electronic materials due to its conjugated heterocyclic system.

Basic Information

Product Name	Ethyl 3-Bromo-1H-Pyrrolo[3,2-B]Pyridine-6-Carboxylate
CAS No.	1956378-91-8
Molecular Formula	C10H9BrN2O2
Molecular Weight	269.10 g/mol
Synonyms	3-Bromo-1H-pyrrolo[3,2-b]pyridine-6-carboxylic acid ethyl ester; Ethyl 3-bromo-1H-pyrrolo[3,2-b]pyridine-6-carboxylate; 1H-Pyrrolo[3,2-b]pyridine-6-carboxylic acid, 3-bromo-, ethyl ester; 3-Bromo-1H-pyrrolo[3,2-b]pyridine-6-carboxylate ethyl ester; 1956378-91-8; 3-Bromo-1H-pyrrolo[3,2-b]pyridine-6-carboxylic acid ethyl ester; 6-Carbethoxy-3-bromo-1H-pyrrolo[3,2-b]pyridine
EINECS	Contact for details

Quality Control

Our Ethyl 3-Bromo-1H-Pyrrolo[3,2-B]Pyridine-6-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.