Description

1H-Indole-1-Carboxylic Acid, 4,6-Dibromo-2,3-Dihydro-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific halogenated indole scaffold. This compound is critical for medicinal chemistry research and development, serving as a key building block for synthesizing novel bioactive molecules. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and CNS drug discovery.

Application

• Pharmaceutical Intermediate: A crucial precursor in the multi-step synthesis of complex drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of new chemical entities.
• Organic Synthesis Building Block: Employed in cross-coupling reactions and further functionalization due to its reactive bromine substituents.
• Biochemical Probe Development: Serves as a starting material for creating labeled compounds or probes used in biological assay development.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for exploratory research in heterocyclic and synthetic organic chemistry.

Basic Information

Product Name	1H-Indole-1-Carboxylic Acid, 4,6-Dibromo-2,3-Dihydro-, 1,1-Dimethylethyl Ester
CAS No.	1956324-96-1
Molecular Formula	C14H15Br2NO2
Molecular Weight	389.08 g/mol
Synonyms	tert-Butyl 4,6-dibromo-2,3-dihydro-1H-indole-1-carboxylate; 4,6-Dibromo-2,3-dihydro-1H-indole-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4,6-dibromo-2,3-dihydroindole; Boc-4,6-dibromo-2,3-dihydroindole; 4,6-Dibromo-N-Boc-2,3-dihydroindole; 4,6-Dibromoindoline-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 1H-Indole-1-Carboxylic Acid, 4,6-Dibromo-2,3-Dihydro-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with complete batch data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.