Description

tert-Butyl ((4-Chloro-1H-Benzo[D]Imidazol-2-Yl)Methyl)Carbamate is a high-purity, advanced pharmaceutical intermediate featuring a protected amine group on a functionalized benzimidazole core. This compound is critical for medicinal chemistry research and development, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the development of new drug candidates, particularly in oncology and antiviral therapeutic areas.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel benzimidazole-based drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize lead compounds for potency and selectivity.
• Protease Inhibitor Development: A potential precursor in the development of inhibitors targeting specific enzymatic pathways.
• Kinase Inhibitor Synthesis: Utilized in the construction of heterocyclic scaffolds for potential kinase inhibitor APIs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Employed in university and institutional labs for exploratory organic synthesis and bio-conjugation studies.

Basic Information

Product Name	tert-Butyl ((4-Chloro-1H-Benzo[D]Imidazol-2-Yl)Methyl)Carbamate
CAS No.	1956322-82-9
Molecular Formula	C₁₄H₁₈ClN₃O₂
Molecular Weight	295.76 g/mol
Synonyms	Boc-4-Chloro-2-aminomethylbenzimidazole; tert-Butyl N-[(4-Chloro-1H-benzimidazol-2-yl)methyl]carbamate; 2-[(tert-Butoxycarbonylamino)methyl]-4-chloro-1H-benzimidazole; 4-Chloro-2-((Boc-amino)methyl)-1H-benzo[d]imidazole; 1H-Benzimidazole-2-methanamine, 4-chloro-, N-Boc derivative; (4-Chloro-1H-benzoimidazol-2-ylmethyl)-carbamic acid tert-butyl ester; BOC-AMINO-METHYL-4-CHLORO-BENZIMIDAZOLE; 1956322-82-9
EINECS	Contact for details

Quality Control

Our tert-Butyl ((4-Chloro-1H-Benzo[D]Imidazol-2-Yl)Methyl)Carbamate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We adhere to ISO 9001 quality management principles, and all products are supported by comprehensive analytical data. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.