Description

Rac-(3Ar,6As)-5-[(tert-Butoxy)Carbonyl]-2,2-Dioxo-Hexahydro-1H-2Lambda6-Thieno[3,4-C]Pyrrole-3A-Carboxylic Acid is a sophisticated, high-purity chemical building block designed for advanced synthetic applications. This compound is critical for researchers and process chemists developing novel active pharmaceutical ingredients (APIs) and other fine chemicals, where precise stereochemistry and functional group compatibility are paramount. Its primary value lies in serving as a key chiral intermediate, enabling the synthesis of complex molecules with high enantiomeric purity for the pharmaceutical and agrochemical industries.

Application

• Pharmaceutical Intermediate: A crucial chiral building block in the research and development of novel Active Pharmaceutical Ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder targets.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides, where specific stereochemistry is essential for bioactivity and environmental safety.
• Asymmetric Catalysis Research: Serves as a valuable ligand precursor or substrate in the development and testing of new asymmetric catalytic systems in academic and industrial R&D.
• Peptidomimetic Chemistry: Employed in the synthesis of peptidomimetics and conformationally constrained peptides for drug discovery programs.
• Chemical Biology Probes: Utilized as a core scaffold for creating molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	Rac-(3Ar,6As)-5-[(tert-Butoxy)Carbonyl]-2,2-Dioxo-Hexahydro-1H-2Lambda6-Thieno[3,4-C]Pyrrole-3A-Carboxylic Acid
CAS No.	1955553-07-7
Molecular Formula	C12H17NO6S
Molecular Weight	303.33 g/mol
Synonyms	5-(tert-Butoxycarbonyl)hexahydro-2λ⁶-thieno[3,4-c]pyrrole-3a(3H)-carboxylic acid 2,2-dioxide (racemic); (3aR,6aS)-rel-5-[(tert-Butoxy)carbonyl]hexahydro-2H-thieno[3,4-c]pyrrole-3a-carboxylic acid 2,2-dioxide; BOC-Protected Hexahydrothienopyrrole Carboxylic Acid S,S-Dioxide; tert-Butyl 3a-carboxy-2,2-dioxohexahydro-1H-thieno[3,4-c]pyrrole-5(6H)-carboxylate; Rac-Boc-Thp(SO2)-OH; Thienopyrrolidine S,S-dioxide derivative; 1955553-07-7
EINECS	Contact for details

Quality Control

Our Rac-(3Ar,6As)-5-[(tert-Butoxy)Carbonyl]-2,2-Dioxo-Hexahydro-1H-2Lambda6-Thieno[3,4-C]Pyrrole-3A-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity suitable for demanding synthetic applications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	Raccemic mixture (50:50)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.