Description

8-Bromo-1,3-Dichloroisoquinoline is a high-value halogenated isoquinoline derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its unique substitution pattern makes it a versatile building block for constructing complex heterocyclic scaffolds with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly those targeting kinase inhibition or other biological pathways where the isoquinoline core is relevant.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or pesticides, leveraging its halogenated structure for bioactivity.
• Material Science: Building block for creating organic electronic materials, ligands for metal-organic frameworks (MOFs), or specialty polymers.
• Chemical Synthesis: Serves as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution for introducing diverse functional groups.
• Academic & R&D: Essential reagent in university and corporate research laboratories for methodological studies and exploring new chemical space.
• Ligand Synthesis: Precursor for the preparation of novel chelating ligands used in catalysis or metal sensing applications.

Basic Information

Product Name	8-Bromo-1,3-Dichloroisoquinoline
CAS No.	1936146-98-3
Molecular Formula	C9H4BrCl2N
Molecular Weight	276.95 g/mol
Synonyms	8-Bromo-1,3-dichloroisoquinoline; Isoquinoline, 8-bromo-1,3-dichloro-; 1,3-Dichloro-8-bromoisoquinoline; 8-Br-1,3-Cl2-Isoquinoline
EINECS	Contact for details

Quality Control

Our 8-Bromo-1,3-Dichloroisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry best practices for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.