Description

4-Bromo-n-Methyl-1H-Pyrrolo[2,3-B]Pyridin-6-Amine is a high-purity, advanced pharmaceutical intermediate belonging to the fused pyrrolopyridine class of heterocyclic compounds. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates targeting a range of therapeutic areas. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of kinase inhibitors and other small-molecule therapeutics.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly in oncology and inflammatory disease pathways.
• Kinase Inhibitor Synthesis: Serves as a core scaffold in the design and synthesis of potent and selective kinase inhibitors due to its privileged heterocyclic structure.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization campaigns to explore new chemical space.
• Bioconjugation & Probe Development: The amine and bromo functional groups allow for further derivatization, making it useful for creating chemical probes and bioconjugates for biological studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and early-phase clinical development.

Basic Information

Item	Details
Product Name	4-Bromo-n-Methyl-1H-Pyrrolo[2,3-B]Pyridin-6-Amine
CAS No.	1935288-47-3
Molecular Formula	C8H8BrN3
Molecular Weight	226.08 g/mol
Synonyms	4-Bromo-6-amino-N-methyl-1H-pyrrolo[2,3-b]pyridine; 4-Bromo-6-amino-1-methyl-1H-pyrrolo[2,3-b]pyridine; 1-Methyl-4-bromo-1H-pyrrolo[2,3-b]pyridin-6-amine; 4-Bromo-1-methyl-1H-pyrrolo[2,3-b]pyridin-6-amine; 6-Amino-4-bromo-1-methyl-1H-pyrrolo[2,3-b]pyridine; 4-Bromo-6-amino-1-methyl-pyrrolo[2,3-b]pyridine; 1935288-47-3
EINECS	Contact for details

Quality Control

Our 4-Bromo-n-Methyl-1H-Pyrrolo[2,3-B]Pyridin-6-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting standards for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.