Description

6-Aza-Bicyclo[3.1.1]Heptan-3-One is a high-purity, advanced pharmaceutical intermediate featuring a unique bridged bicyclic structure. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and metabolic disorder research pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates and novel bioactive molecules.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Proteolysis Targeting Chimera (PROTAC) Development: Used in the construction of linkers or warheads for targeted protein degradation therapeutics.
• Agrochemical Synthesis: Potential application as an intermediate in the development of new pesticides or herbicides with novel modes of action.
• Academic & Contract Research: Employed in university and CRO settings for methodological development and the exploration of new chemical spaces.

Basic Information

Product Name	6-Aza-Bicyclo[3.1.1]Heptan-3-One
CAS No.	1935211-35-0
Molecular Formula	C6H9NO
Molecular Weight	111.14 g/mol
Synonyms	6-Azabicyclo[3.1.1]heptan-3-one; 3-Oxo-6-azabicyclo[3.1.1]heptane; 6-Aza-bicyclo[3.1.1]heptan-3-one; 1-Aza-4-oxatricyclo[3.3.1.02,7]nonane (alternative systematic name); Bridged azetidinone derivative; 6-Azabicyclo[3.1.1]heptane-3-one
EINECS	Contact for details

Quality Control

Our 6-Aza-Bicyclo[3.1.1]Heptan-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles suitable for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.