Description

8-Bromo-6-Fluoroisoquinoline is a high-value, halogenated isoquinoline derivative serving as a critical building block in advanced organic synthesis. Its unique molecular architecture, featuring both bromine and fluorine substituents, makes it an indispensable intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other therapeutic agents.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging the bioactivity-modifying properties of the halogenated isoquinoline core.
• Material Science: Serves as a monomer or functional unit in the creation of advanced organic electronic materials, such as OLEDs and semiconductors.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions due to the reactivity of the bromine atom.
• Ligand & Catalyst Development: Utilized for constructing novel chelating ligands for metal catalysts used in asymmetric synthesis.
• Life Science Research: Acts as a fluorescent probe or a tag in biochemical assays and diagnostic development.

Basic Information

Item	Detail
Product Name	8-Bromo-6-Fluoroisoquinoline
CAS No.	1935199-41-9
Molecular Formula	C9H5BrFN
Molecular Weight	226.05 g/mol
Synonyms	6-Fluoro-8-bromoisoquinoline; 8-Bromo-6-fluoro-isoquinoline; Isoquinoline, 8-bromo-6-fluoro-; 1935199-41-9
EINECS	Contact for details

Quality Control

Our 8-Bromo-6-Fluoroisoquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere for prolonged stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.