Description

7-Bromo-5-Methyl-3,4-Dihydroisoquinolin-1(2H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the isoquinolinone class of heterocyclic compounds. This compound is a critical building block in modern organic synthesis, valued for its unique brominated and methylated structure which enables precise molecular modifications. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. Our supply is characterized by stringent quality control and reliable batch-to-batch consistency to support demanding R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its heterocyclic core for biological activity.
• Material Science: Acts as a monomer or functional additive in the research of advanced polymers and organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic chemistry and medicinal chemistry.
• Chemical Biology: Utilized as a molecular probe or scaffold in the design of enzyme inhibitors and receptor ligands.

Basic Information

Product Name	7-Bromo-5-Methyl-3,4-Dihydroisoquinolin-1(2H)-One
CAS No.	1934975-00-4
Molecular Formula	C₁₀H₁₀BrNO
Molecular Weight	240.10 g/mol
Synonyms	7-Bromo-5-methyl-3,4-dihydro-1H-isoquinolin-1-one; 7-Bromo-5-methyl-1,2,3,4-tetrahydroisoquinolin-1-one; 1(2H)-Isoquinolinone, 7-bromo-3,4-dihydro-5-methyl-; 1934975-00-4; 7-Bromo-5-methyl-1-oxo-1,2,3,4-tetrahydroisoquinoline
EINECS	Contact for details

Quality Control

Our production of 7-Bromo-5-Methyl-3,4-Dihydroisoquinolin-1(2H)-One adheres to a strict quality management system. Every batch is analyzed using advanced techniques including HPLC, GC, and NMR to ensure identity, purity, and conformity to client specifications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP principles and ISO 9001 standards ensures a reliable and traceable supply chain for our global partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. Handle and store in accordance with all applicable local and international regulations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.