Description

Methyl 4-(Bromomethyl)Bicyclo[2.2.2]Octane-1-Carboxylate is a high-value, functionalized bicyclic building block designed for advanced organic synthesis. This compound matters for its unique rigid scaffold and reactive bromomethyl handle, enabling precise molecular construction in complex chemical environments. It is primarily needed by researchers and process chemists in the pharmaceutical and agrochemical industries for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies, leveraging its rigid bicyclo[2.2.2]octane core.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structural stability can enhance product performance and environmental persistence.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the synthesis of monomers for high-performance polymers, liquid crystals, and other advanced materials requiring rigid, three-dimensional structures.
• Chemical Biology Probe Synthesis: Utilized to create molecular probes and tags for studying biological systems and protein interactions.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and C-H functionalization.

Basic Information

Product Name	Methyl 4-(Bromomethyl)Bicyclo[2.2.2]Octane-1-Carboxylate
CAS No.	1934962-73-8
Molecular Formula	C12H19BrO2
Molecular Weight	275.18 g/mol
Synonyms	Methyl 4-(bromomethyl)bicyclo[2.2.2]octane-1-carboxylate; 1-(Bromomethyl)bicyclo[2.2.2]octane-4-carboxylic acid methyl ester; 4-(Bromomethyl)bicyclo[2.2.2]octane-1-carboxylic acid methyl ester; Bicyclo[2.2.2]octane-1-carboxylic acid, 4-(bromomethyl)-, methyl ester; Methyl 4-(bromomethyl)-1-bicyclo[2.2.2]octanecarboxylate
EINECS	Contact for details

Quality Control

Our Methyl 4-(Bromomethyl)Bicyclo[2.2.2]Octane-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance for research and scale-up applications. Certificates of Analysis (COA) with full characterization data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged operations.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.