Description

3-(Aminomethyl)Bicyclo[1.1.1]Pentane-1-Carbonitrile is a high-value, structurally constrained bicyclic building block featuring both amine and nitrile functional groups. This compound matters as a key intermediate for medicinal chemistry, enabling the synthesis of novel, three-dimensional scaffolds with improved physicochemical properties for drug discovery. Pharmaceutical researchers and agrochemical developers need it to create new active ingredients with enhanced metabolic stability and target selectivity.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing novel drug candidates, particularly in fragment-based drug discovery and for creating bioisosteres of benzene rings.
• Agrochemical Research: Used in the development of new pesticides and herbicides with unique modes of action and improved environmental profiles.
• Material Science: Serves as a precursor for specialty polymers and advanced materials requiring rigid, three-dimensional molecular architectures.
• Chemical Biology: Employed in the synthesis of probes and tool compounds for studying enzyme function and protein-protein interactions.
• Peptidomimetics: Facilitates the creation of constrained peptide analogs with enhanced stability and bioavailability.
• Ligand Synthesis: Used to prepare novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-(Aminomethyl)Bicyclo[1.1.1]Pentane-1-Carbonitrile
CAS No.	1934858-95-3
Molecular Formula	C8H10N2
Molecular Weight	134.18 g/mol
Synonyms	1-Cyano-3-(aminomethyl)bicyclo[1.1.1]pentane; 3-(Aminomethyl)-1-cyanobicyclo[1.1.1]pentane; Bicyclo[1.1.1]pentane-1-carbonitrile, 3-(aminomethyl)-; [1.1.1]Propellane-3-methanamine, 1-cyano-; 3-Aminomethylbicyclo[1.1.1]pentane-1-carbonitrile; Aminomethyl-BCP-carbonitrile; BCP-Nitrile-amine
EINECS	Contact for details

Quality Control

Our 3-(Aminomethyl)Bicyclo[1.1.1]Pentane-1-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.