Description

4-Bromo-5-Nitro-1H-Indole is a halogenated nitroindole derivative, a versatile and high-value synthetic building block in advanced organic chemistry. Its unique structure, featuring both bromine and nitro substituents on the indole core, makes it a critical intermediate for constructing complex molecules with tailored electronic and biological properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for the synthesis of novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors, receptor modulators, and other biologically active indole-based molecules.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators where the indole scaffold is a core structural motif.
• Material Science: Acts as a building block for organic semiconductors, dyes, and photoactive materials due to its electron-withdrawing nitro group and potential for further functionalization.
• Chemical Biology & Proteomics: Employed in the design and synthesis of molecular probes, tags, and activity-based probes for studying biological systems.
• Academic & Contract Research: Essential for methodological development, library synthesis, and discovery chemistry in university and CRO laboratory settings.
• Custom Synthesis: A starting point for the tailored synthesis of more complex, multi-functional indole derivatives for specialized client applications.

Basic Information

Product Name	4-Bromo-5-Nitro-1H-Indole
CAS No.	1934562-99-8
Molecular Formula	C8H5BrN2O2
Molecular Weight	241.04 g/mol
Synonyms	4-Bromo-5-nitroindole; 1H-Indole, 4-bromo-5-nitro-; 5-Nitro-4-bromoindole; 4-Bromo-5-nitro-1H-indole; 4-Br-5-NO2-indole
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Nitro-1H-Indole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) with batch-specific data is provided with each shipment to guarantee traceability, consistency, and reliability for your critical synthetic workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	Yellow to brown powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.