Description

(Meso-1R,5S,9S)-tert-Butyl 9-Amino-3-Oxa-7-Azabicyclo[3.3.1]Nonane-7-Carboxylate (Wx120552) is a high-purity, advanced pharmaceutical intermediate featuring a unique, rigid bicyclic scaffold. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) and antiviral therapeutics. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in process development and scale-up of novel drug candidates.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex drug molecules, especially those targeting neurological pathways.
• Process Chemistry & Scale-Up: Used in route scouting and optimization for the commercial manufacturing of APIs requiring its specific stereochemistry and bicyclic structure.
• Medicinal Chemistry Research: Serves as a versatile scaffold in drug discovery programs for creating novel chemical libraries and lead optimization.
• Asymmetric Synthesis: Employed in catalytic and stoichiometric asymmetric transformations due to its defined stereocenters and functional handles.
• Peptidomimetic Development: Its constrained 3-oxa-7-azabicyclo[3.3.1]nonane core is valuable for designing conformationally restricted peptide analogs.

Basic Information

Product Name	(Meso-1R,5S,9S)-tert-Butyl 9-Amino-3-Oxa-7-Azabicyclo[3.3.1]Nonane-7-Carboxylate (Wx120552)
CAS No.	1932441-42-3
Molecular Formula	C12H22N2O3
Molecular Weight	242.32 g/mol
Synonyms	tert-Butyl (1R,5S,9S)-9-amino-3-oxa-7-azabicyclo[3.3.1]nonane-7-carboxylate; 7-Boc-9-amino-3-oxa-7-azabicyclo[3.3.1]nonane; 3-Oxa-7-azabicyclo[3.3.1]nonane-7-carboxylic acid, 9-amino-, 1,1-dimethylethyl ester, (1R,5S,9S)-; Wx120552; Bicyclic amino ester Boc-protected; (Meso)-Boc-protected 9-amino-3-oxa-7-azabicyclononane.
EINECS	Contact for details

Quality Control

Our (Meso-1R,5S,9S)-tert-Butyl 9-Amino-3-Oxa-7-Azabicyclo[3.3.1]Nonane-7-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and chiral purity suitable for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label or COA. This material is hygroscopic (moisture-sensitive) and should be handled under a dry inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.