Description

(1R,6R)-7-Cbz-3,7-Diazabicyclo[4.2.0]Octane is a high-purity, advanced pharmaceutical intermediate featuring a constrained diazabicyclic scaffold. This compound is a critical chiral building block for the synthesis of complex bioactive molecules, offering significant value in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel therapeutics, particularly in areas requiring rigid, nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs).
• Medicinal Chemistry: Used in the construction of complex molecular architectures for drug discovery programs, especially for central nervous system (CNS) and infectious disease targets.
• Process Chemistry: Serves as a starting material or intermediate in the scale-up and optimization of synthetic routes for candidate drugs.
• Chemical Biology: Employed as a probe or scaffold in the study of enzyme inhibition and receptor-ligand interactions.
• Academic Research: Utilized in synthetic organic chemistry research to develop new methodologies for heterocycle formation and functionalization.

Basic Information

Product Name	(1R,6R)-7-Cbz-3,7-Diazabicyclo[4.2.0]Octane
CAS No.	1932046-84-8
Molecular Formula	C15H20N2O2
Molecular Weight	260.33 g/mol
Synonyms	(1R,6R)-7-[(Benzyloxy)carbonyl]-3,7-diazabicyclo[4.2.0]octane; (1R,6R)-7-Carbobenzoxy-3,7-diazabicyclo[4.2.0]octane; (1R,6R)-7-Cbz-3,7-diazabicyclo[4.2.0]octane; (1R,6R)-7-(N-Cbz)-3,7-diazabicyclo[4.2.0]octane; Cbz-Protected (1R,6R)-3,7-Diazabicyclo[4.2.0]octane; (1R,6R)-3,7-Diazabicyclo[4.2.0]octane-7-carboxylic acid benzyl ester; Benzyl (1R,6R)-3,7-diazabicyclo[4.2.0]octane-7-carboxylate
EINECS	Contact for details

Quality Control

Our (1R,6R)-7-Cbz-3,7-Diazabicyclo[4.2.0]Octane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with research-grade specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity (by HPLC), and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.