Description

Ethyl 5-Bromo-6-Chloro-1H-Indole-2-Carboxylate is a high-purity, multi-halogenated indole derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile and functionalized scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the bioactivity of the halogenated indole core.
• Material Science: Serves as a monomer or functional unit in the creation of specialized polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or tag in biochemical assays and for studying protein-ligand interactions.
• Academic & Contract Research: Utilized in university and CRO laboratories for method development and exploring new chemical spaces in heterocyclic chemistry.

Basic Information

Product Name	Ethyl 5-Bromo-6-Chloro-1H-Indole-2-Carboxylate
CAS No.	1923237-13-1
Molecular Formula	C11H9BrClNO2
Molecular Weight	302.55 g/mol
Synonyms	5-Bromo-6-chloro-1H-indole-2-carboxylic acid ethyl ester; Ethyl 5-bromo-6-chloroindole-2-carboxylate; 1H-Indole-2-carboxylic acid, 5-bromo-6-chloro-, ethyl ester; 1923237-13-1; 5-Bromo-6-chloroindole-2-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Every batch of Ethyl 5-Bromo-6-Chloro-1H-Indole-2-Carboxylate is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications, which are aligned with industry best practices for advanced pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.