Description

4-Bromo-5-Fluoro-2,3-Dimethyl-1H-Indole-7-Carbonitrile is a high-value, multi-functional indole derivative that serves as a critical building block in advanced organic synthesis. Its unique halogenated and nitrile-substituted structure makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used to develop new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Serves as a monomer or functional unit in the creation of advanced organic electronic materials and specialty polymers.
• Chemical Biology: Employed as a molecular probe or tag in biochemical research and assay development.
• Academic & Industrial R&D: A versatile scaffold for method development and exploration of new chemical reactions in heterocyclic chemistry.

Basic Information

Product Name	4-Bromo-5-Fluoro-2,3-Dimethyl-1H-Indole-7-Carbonitrile
CAS No.	1912446-10-6
Molecular Formula	C11H8BrFN2
Molecular Weight	267.10 g/mol
Synonyms	7-Cyano-4-bromo-5-fluoro-2,3-dimethyl-1H-indole; 4-Bromo-5-fluoro-2,3-dimethyl-1H-indole-7-carbonitrile; 1H-Indole-7-carbonitrile, 4-bromo-5-fluoro-2,3-dimethyl-; 4-Bromo-5-fluoro-2,3-dimethylindole-7-carbonitrile
EINECS	Contact for details

Quality Control

Our 4-Bromo-5-Fluoro-2,3-Dimethyl-1H-Indole-7-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere if specified. Keep away from strong acids/bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.