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3-(tert-Butyl)-4-(2,6-Dimethoxyphenyl)-2-(2,4,6-Triisopropylbenzyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphole CAS NO 1908442-13-6


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CAS No.:1908442-13-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-(tert-Butyl)-4-(2,6-Dimethoxyphenyl)-2-(2,4,6-Triisopropylbenzyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphole is a sophisticated, sterically hindered organophosphorus compound, specifically a dihydrobenzooxaphosphole derivative, valued for its unique electronic and steric properties. This compound is a critical specialty chemical intermediate in advanced organic synthesis, particularly in the development of novel ligands and catalysts for asymmetric transformations. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams working on complex molecular architectures.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of complex active pharmaceutical ingredients (APIs), especially those requiring chiral induction.
  • Catalyst & Ligand Precursor: Serves as a precursor for the development of novel phosphine-based ligands used in transition metal catalysis (e.g., cross-coupling, hydrogenation).
  • Material Science Research: Used in the development of organic electronic materials and functional polymers where specific phosphorus-containing motifs are required.
  • Agrochemical Synthesis: An intermediate in the research and production of advanced crop protection agents with novel modes of action.
  • Academic & Industrial R&D: A valuable reagent for methodological development in organic chemistry, enabling new synthetic pathways.

Basic Information

Product Name 3-(tert-Butyl)-4-(2,6-Dimethoxyphenyl)-2-(2,4,6-Triisopropylbenzyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphole
CAS No. 1908442-13-6
Molecular Formula C34H45O3P
Molecular Weight 532.70 g/mol
Synonyms 2,3-Dihydrobenzo[d][1,3]oxaphosphole, 3-(1,1-dimethylethyl)-4-(2,6-dimethoxyphenyl)-2-[(2,4,6-triisopropylphenyl)methyl]-; 3-tert-Butyl-4-(2,6-dimethoxyphenyl)-2-(2,4,6-triisopropylbenzyl)-2,3-dihydrobenzo[d][1,3]oxaphosphole; Dihydrobenzooxaphosphole derivative CAS 1908442-13-6; Sterically hindered phosphine ligand precursor; Triisopropylbenzyl-substituted benzooxaphosphole
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Quality Control

Every batch of our 3-(tert-Butyl)-4-(2,6-Dimethoxyphenyl)-2-(2,4,6-Triisopropylbenzyl)-2,3-Dihydrobenzo[D][1,3]Oxaphosphole is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, supporting compliance with cGMP and ISO standards for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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