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Boronic Acid, B-(2-Methyl[1,1'-Biphenyl]-3-Yl)- CAS NO 1899060-83-3


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CAS No.:1899060-83-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Boronic Acid, B-(2-Methyl[1,1'-Biphenyl]-3-Yl)- is a specialized biphenyl-substituted boronic acid derivative, a crucial building block in modern synthetic chemistry. Its primary value lies in its role as a key coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl structures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and advanced materials.

Application

  • Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those containing biphenyl or substituted biphenyl moieties.
  • Suzuki-Miyaura Cross-Coupling: Serves as a versatile boronic acid reagent for palladium-catalyzed carbon-carbon bond formation to create complex biaryl systems.
  • Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require specific biphenyl scaffolds.
  • Material Science: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs and other functional polymers.
  • Chemical Synthesis: Acts as a building block for creating more complex molecules in academic and industrial R&D laboratories.
  • Ligand Synthesis: Useful for preparing specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name Boronic Acid, B-(2-Methyl[1,1'-Biphenyl]-3-Yl)-
CAS No. 1899060-83-3
Molecular Formula C19H17BO2
Molecular Weight 288.15 g/mol
Synonyms (2-Methyl-[1,1'-biphenyl]-3-yl)boronic acid; 3-Borono-2-methylbiphenyl; 2-Methylbiphenyl-3-boronic acid; B-(2-Methyl[1,1'-biphenyl]-3-yl)boronic acid; 2'-Methyl-[1,1'-biphenyl]-3-boronic acid; [1,1'-Biphenyl]-3-boronic acid, 2-methyl-; 3-(2-Methylphenyl)phenylboronic acid
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Quality Control

Our Boronic Acid, B-(2-Methyl[1,1'-Biphenyl]-3-Yl)- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for sensitive applications like pharmaceutical synthesis. Each lot is analyzed using advanced techniques including HPLC, NMR, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Water Content (KF) ≤ 0.5%
Heavy Metals ≤ 20 ppm
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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