Description

3-(1,1-Difluoroethyl)-Benzenethiol is a specialized organosulfur compound featuring a difluoroethyl substituent on the benzene ring. This structure makes it a valuable building block for introducing sulfur and fluorine motifs into target molecules, which are critical for modulating the physicochemical and biological properties of advanced materials and pharmaceuticals. It is primarily sought by research and development chemists in the agrochemical and pharmaceutical industries for applications in medicinal chemistry, material science, and as a ligand precursor in catalysis.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for introducing lipophilic and metabolically stable motifs.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the fluorine and sulfur groups can enhance biological activity and environmental stability.
• Material Science Precursor: Acts as a monomer or functionalization agent in the synthesis of specialty polymers, liquid crystals, and electronic materials.
• Catalysis & Ligand Design: Employed in the development of novel organocatalysts and metal-organic complexes where the thiol group acts as a coordinating ligand.
• Chemical Research (R&D): Utilized in academic and industrial laboratories for exploring new synthetic methodologies and fluorine chemistry.

Basic Information

Product Name	3-(1,1-Difluoroethyl)-Benzenethiol
CAS No.	1896970-19-6
Molecular Formula	C8H8F2S
Molecular Weight	174.21 g/mol
Synonyms	3-(1,1-Difluoroethyl)benzenethiol; 3-(1,1-Difluoroethyl)thiophenol; 1-(1,1-Difluoroethyl)-3-mercaptobenzene; m-(1,1-Difluoroethyl)thiophenol; Benzenethiol, 3-(1,1-difluoroethyl)-; α,α-Difluoro-3-mercaptoethylbenzene
EINECS	Contact for details

Quality Control

Our production of 3-(1,1-Difluoroethyl)-Benzenethiol adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity for research and industrial use. Quality is verified through analytical techniques including GC, HPLC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C or as specified on the label. This compound is easily oxidized and should be handled in a controlled environment to maintain stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.