Description

8-Bromo-4-Chloroisoquinoline is a high-purity halogenated isoquinoline derivative, a crucial building block in advanced organic synthesis. Its value lies in its dual reactive sites, which enable precise functionalization for creating complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting kinases and other enzymatic pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the isoquinoline scaffold's bioactivity.
• Material Science: Acts as a monomer or functionalizing agent in the creation of specialty polymers, ligands, and organic electronic materials.
• Chemical Biology: Employed as a probe or tag in biochemical assays and for studying protein-ligand interactions.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the bromo and chloro substituents.
• Academic & Contract Research: Essential for methodological development and discovery chemistry in university and CRO laboratories.

Basic Information

Product Name	8-Bromo-4-Chloroisoquinoline
CAS No.	1895964-91-6
Molecular Formula	C9H5BrClN
Molecular Weight	242.50 g/mol
Synonyms	4-Chloro-8-bromoisoquinoline; 8-Bromo-4-chloro-isoquinoline; Isoquinoline, 8-bromo-4-chloro-; 1895964-91-6
EINECS	Contact for details

Quality Control

Our 8-Bromo-4-Chloroisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.