Description

1H-Indazole-6-Carboxaldehyde, 4-Fluoro- is a high-purity fluorinated indazole derivative, serving as a critical advanced pharmaceutical intermediate. Its value lies in providing a versatile aldehyde functional group on a fluorinated heterocyclic scaffold, enabling precise molecular construction for targeted drug discovery. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on synthesizing novel kinase inhibitors, anti-cancer agents, and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially kinase inhibitors and targeted oncology therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the biological activity of the fluorinated indazole core.
• Chemical Biology: Serves as a probe or linker in the development of biochemical tools and diagnostic agents due to its reactive aldehyde group.
• Material Science: Potential precursor for specialty polymers or organic electronic materials requiring specific heterocyclic architectures.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	1H-Indazole-6-Carboxaldehyde, 4-Fluoro-
CAS No.	1893909-76-6
Molecular Formula	C8H5FN2O
Molecular Weight	164.14 g/mol
Synonyms	4-Fluoro-1H-indazole-6-carboxaldehyde; 4-Fluoro-1H-indazole-6-carbaldehyde; 6-Formyl-4-fluoro-1H-indazole; 4-Fluoroindazole-6-carboxaldehyde; 1893909-76-6; 4-Fluoro-1H-indazole-6-carboxaldehyde (CAS 1893909-76-6); 4-Fluoro-1H-indazole-6-carbaldehyde (CAS 1893909-76-6)
EINECS	Contact for details

Quality Control

Every batch of 1H-Indazole-6-Carboxaldehyde, 4-Fluoro- is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is easily oxidized (store under inert atmosphere) and is light-sensitive (store away from light). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.