Description

5-(5-((1R,2S)-2-Amino-3-Methyl-1-Phenylbutoxy)-1H-Indazol-1-Yl)-1-Methylpyridin-2(1H)-One is a high-purity, advanced pharmaceutical intermediate with a complex, chiral molecular structure. This compound is critical for research and development in medicinal chemistry, particularly for its potential role as a key building block in novel therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories, biotechnology companies, and contract research organizations (CROs) engaged in the synthesis of targeted small-molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral building block in the multi-step synthesis of investigational new drugs (INDs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic targets.
• API Development: A potential precursor in the development of active pharmaceutical ingredients (APIs) for clinical trials.
• Biochemical Tool Compound: May be utilized in biochemical assays to study specific enzyme or receptor interactions.
• Process Chemistry: Employed in route scouting and scale-up process development for complex organic molecules.
• Academic Research: Used in university and institutional labs for advanced synthetic organic chemistry and pharmacology studies.

Basic Information

Product Name	5-(5-((1R,2S)-2-Amino-3-Methyl-1-Phenylbutoxy)-1H-Indazol-1-Yl)-1-Methylpyridin-2(1H)-One
CAS No.	1893415-32-1
Molecular Formula	C25H28N4O2
Molecular Weight	416.52 g/mol
Synonyms	1-Methyl-5-[5-[(1R,2S)-2-amino-3-methyl-1-phenylbutoxy]-1H-indazol-1-yl]pyridin-2(1H)-one; (1R,2S)-2-Amino-3-methyl-1-phenylbutyl 1-(1-methyl-6-oxo-1,6-dihydropyridin-3-yl)-1H-indazol-5-yl ether; CAS 1893415-32-1; 5-(5-((1R,2S)-2-Amino-3-methyl-1-phenylbutoxy)-1H-indazol-1-yl)-1-methylpyridin-2(1H)-one; 1-Methyl-5-(5-((1R,2S)-2-amino-3-methyl-1-phenylbutoxy)-1H-indazol-1-yl)pyridin-2(1H)-one
EINECS	Contact for details

Quality Control

Our 5-(5-((1R,2S)-2-Amino-3-Methyl-1-Phenylbutoxy)-1H-Indazol-1-Yl)-1-Methylpyridin-2(1H)-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.