Description

6-Chloro-1H-Indazole-5-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its indazole core structure with chloro and carboxylic acid functional groups. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and fine chemical manufacturers seeking to develop new therapeutic agents and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating novel herbicides, fungicides, or plant growth regulators.
• Biochemical Tool Compound: Utilized in biochemical assays and as a probe for studying enzyme inhibition or receptor binding.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals and dyes.
• Academic & Contract Research: Supplied to universities and CROs (Contract Research Organizations) for exploratory chemical research.

Basic Information

Product Name	6-Chloro-1H-Indazole-5-Carboxylic Acid
CAS No.	1890961-61-1
Molecular Formula	C8H5ClN2O2
Molecular Weight	196.59 g/mol
Synonyms	6-Chloro-1H-indazole-5-carboxylic acid; 5-Carboxy-6-chloro-1H-indazole; 6-Chloro-5-indazolecarboxylic acid; 1H-Indazole-5-carboxylic acid, 6-chloro-; 1890961-61-1; 6-Chloroindazole-5-carboxylic acid
EINECS	Contact for details

Quality Control

Our 6-Chloro-1H-Indazole-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.