Description

5-(5-Methoxybenzo[B]Thiophen-2-Yl)-1H-Pyrrole-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or oncological pathways.
• Organic Synthesis Building Block: Used in research-scale and pilot-scale organic reactions, including cross-coupling and cyclization, to construct complex heterocyclic systems.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in academic and industrial R&D laboratories.
• Process Chemistry Development: Employed in the optimization and scale-up of synthetic routes for potential new chemical entities (NCEs).
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Item	Details
Product Name	5-(5-Methoxybenzo[B]Thiophen-2-Yl)-1H-Pyrrole-2-Carboxylic Acid
CAS No.	1889802-11-2
Molecular Formula	C15H11NO3S
Molecular Weight	285.32 g/mol
Synonyms	5-(5-Methoxybenzo[b]thiophen-2-yl)-1H-pyrrole-2-carboxylic acid; 5-(5-Methoxy-1-benzothiophen-2-yl)-1H-pyrrole-2-carboxylic acid; 1H-Pyrrole-2-carboxylic acid, 5-(5-methoxybenzo[b]thien-2-yl)-; 1889802-11-2; 5-(5-Methoxybenzo[b]thien-2-yl)-1H-pyrrole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 5-(5-Methoxybenzo[B]Thiophen-2-Yl)-1H-Pyrrole-2-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect stability and handling properties. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.