Description

(R)-2-Amino-4-(2-((4-(2-((2-Hydroxy-2-Phenylethyl)Amino)Ethyl) Phenyl)Amino)-2-Oxoethyl)Thiazole 3-Oxide is a sophisticated chiral organic compound featuring a thiazole oxide core with multiple functionalized aromatic and amino substituents. This complex molecular architecture makes it a valuable advanced pharmaceutical intermediate (API) and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of novel therapeutic agents, particularly those targeting central nervous system (CNS) disorders and other specialized disease areas.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel drug candidates, particularly for CNS-targeting therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for developing new active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Serves as a chiral precursor or ligand in catalytic asymmetric reactions due to its defined (R)-configuration.
• Biochemical Probe Development: Potential use in creating labeled compounds or probes for studying biological pathways and receptor interactions.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale manufacturing of complex molecules.
• Academic & Institutional Research: Used in universities and research institutes for cutting-edge organic synthesis and drug discovery projects.

Basic Information

Product Name	(R)-2-Amino-4-(2-((4-(2-((2-Hydroxy-2-Phenylethyl)Amino)Ethyl) Phenyl)Amino)-2-Oxoethyl)Thiazole 3-Oxide
CAS No.	1884646-38-1
Molecular Formula	C21H24N4O3S
Molecular Weight	412.51 g/mol
Synonyms	(R)-2-Amino-4-[2-[[4-[2-[(2-Hydroxy-2-phenylethyl)amino]ethyl]phenyl]amino]-2-oxoethyl]-1,3-thiazole 3-Oxide; 2-Amino-4-(2-((4-(2-((2-hydroxy-2-phenylethyl)amino)ethyl)phenyl)amino)-2-oxoethyl)thiazole 3-oxide, (R)-; (R)-enantiomer of the thiazole N-oxide derivative; (R)-ATPO derivative; Chiral thiazole oxide amine; 1884646-38-1; SCHEMBL23545417
EINECS	Contact for details

Quality Control

Our (R)-2-Amino-4-(2-((4-(2-((2-Hydroxy-2-Phenylethyl)Amino)Ethyl) Phenyl)Amino)-2-Oxoethyl)Thiazole 3-Oxide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis (HPLC), to ensure high chemical and enantiomeric purity suitable for advanced research and development. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability and purity. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.