Description

(4-Bromothiophen-3-Yl)(Pyrrolidin-1-Yl)Methanone is a high-purity, advanced pharmaceutical intermediate featuring a brominated thiophene core linked to a pyrrolidine amide. This compound is specifically engineered for its role as a critical building block in modern medicinal chemistry, enabling the synthesis of novel bioactive molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel active ingredients for crop protection products, leveraging its unique heterocyclic structure.
• Material Science Precursor: Serves as a specialized monomer or precursor for the development of organic electronic materials and functional polymers.
• Chemical Biology Probe Development: Employed in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects requiring this precise molecular architecture.

Basic Information

Product Name	(4-Bromothiophen-3-Yl)(Pyrrolidin-1-Yl)Methanone
CAS No.	1872849-86-9
Molecular Formula	C9H10BrNOS
Molecular Weight	260.15 g/mol
Synonyms	1-(4-Bromothiophen-3-yl)-1-pyrrolidinylmethanone; 1-(4-Bromo-3-thienyl)-1-pyrrolidinylmethanone; (4-Bromo-3-thienyl)(pyrrolidin-1-yl)methanone; 4-Bromo-3-(1-pyrrolidinylcarbonyl)thiophene; 4-Bromo-3-pyrrolidine-1-carbonylthiophene; 3-Pyrrolidin-1-ylcarbonyl-4-bromothiophene; 4-Bromo-3-thiophenecarboxylic acid pyrrolidide
EINECS	Contact for details

Quality Control

Our production of (4-Bromothiophen-3-Yl)(Pyrrolidin-1-Yl)Methanone adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All material is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support development and commercial projects with specifications that can meet the rigorous standards required for pharmaceutical R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.