Description

3-(2-Aminoacetyl)-2,5-Dibromothiophene Hydrochloride is a high-purity, halogenated thiophene derivative with a reactive aminoacetyl functional group. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily required by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and insecticides, leveraging the thiophene and bromine motifs for bioactivity.
• Material Science: Monomer or precursor for conductive polymers and organic electronic materials due to the thiophene backbone.
• Organic Synthesis: Versatile reagent for cross-coupling reactions (e.g., Suzuki, Stille) and as a scaffold for heterocyclic chemistry, enabling the creation of diverse compound libraries.
• Chemical Biology: Used in the development of molecular probes and enzyme inhibitors for biochemical research.

Basic Information

Product Name	3-(2-Aminoacetyl)-2,5-Dibromothiophene Hydrochloride
CAS No.	1864060-98-9
Molecular Formula	C6H5Br2ClNO2S
Molecular Weight	355.43 g/mol
Synonyms	2,5-Dibromo-3-(2-aminoacetyl)thiophene hydrochloride; 2-Acetamido-3,5-dibromothiophene Hydrochloride; 3-(2-Aminoacetyl)-2,5-dibromothiophene HCl; 2,5-Dibromo-3-glycylthiophene hydrochloride; 1864060-98-9; Aminoacetyl dibromothiophene HCl; Thiophene-3-glycine derivative, 2,5-dibromo-, hydrochloride
EINECS	Contact for details

Quality Control

Every batch of 3-(2-Aminoacetyl)-2,5-Dibromothiophene Hydrochloride is manufactured under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high standards required for research and development. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment. Our quality protocols are designed to support GMP/GLP-compliant research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.