Description

4-Bromothiophen-3-Amine Hydrochloride is a high-purity organic building block essential for advanced pharmaceutical and agrochemical research and development. This compound serves as a critical intermediate in the synthesis of complex molecules, particularly those containing the thiophene heterocycle, which is valued for its electronic and biological properties. It is primarily utilized by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting CNS disorders, oncology, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the thiophene moiety for bioactivity.
• Material Science Research: Serves as a precursor for the development of organic semiconductors, conductive polymers, and non-linear optical materials.
• Chemical Biology: Employed as a molecular probe or linker in the study of biological processes and the development of diagnostic agents.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds for clients.

Basic Information

Product Name	4-Bromothiophen-3-Amine Hydrochloride
CAS No.	1864015-49-5
Molecular Formula	C4H5BrClNS
Molecular Weight	222.51 g/mol
Synonyms	3-Amino-4-bromothiophene hydrochloride; 4-Bromo-3-aminothiophene hydrochloride; 4-Bromothiophen-3-amine HCl; 3-Thiophenamine, 4-bromo-, hydrochloride; 4-Bromo-3-thiophenamine hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Bromothiophen-3-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from moisture and light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.