Description

(+/-)-trans-4-(3-Thienyl)-Pyrrolidine-3-Carboxylic Acid-Hcl CAS NO 1864003-47-3 is a high-purity, heterocyclic organic compound featuring a pyrrolidine core substituted with a thienyl group and a carboxylic acid functionality. This compound matters as a versatile and valuable pharmaceutical intermediate and chiral building block for medicinal chemistry research and drug development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Building Block: Used in structure-activity relationship (SAR) studies and for the synthesis of compound libraries for high-throughput screening.
• Ligand Synthesis: Serves as a precursor for creating complex ligands used in catalysis and molecular recognition.
• Agrochemical Research: Employed in the development of novel pesticides and herbicides due to its unique heterocyclic structure.
• Academic & Contract Research: Utilized in university and CRO (Contract Research Organization) laboratories for fundamental organic synthesis and methodological studies.
• Peptidomimetic Development: The pyrrolidine-carboxylic acid scaffold is valuable for designing peptide mimics with enhanced metabolic stability.

Basic Information

Item	Detail
Product Name	(+/-)-trans-4-(3-Thienyl)-Pyrrolidine-3-Carboxylic Acid Hydrochloride
CAS No.	1864003-47-3
Molecular Formula	C9H12ClNO2S
Molecular Weight	233.71 g/mol
Synonyms	trans-4-(Thiophen-3-yl)pyrrolidine-3-carboxylic acid hydrochloride; 3-Thiophenepyrrolidine-3-carboxylic acid, 4-(3-thienyl)-, hydrochloride, trans-; 4-(3-Thienyl)-3-pyrrolidinecarboxylic acid hydrochloride, trans-; 4-(Thiophen-3-yl)pyrrolidine-3-carboxylic acid HCl; Pyrrolidine-3-carboxylic acid, 4-(3-thienyl)-, hydrochloride, trans-; 1864003-47-3; (trans)-4-(3-Thienyl)pyrrolidine-3-carboxylic acid hydrochloride
EINECS	Contact for details

Quality Control

Our (+/-)-trans-4-(3-Thienyl)-Pyrrolidine-3-Carboxylic Acid-Hcl is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.