Description

1-Methyl-Cyclopropylboronic Acid is a specialized organoboron compound of significant interest in modern synthetic chemistry. This boronic acid derivative serves as a crucial building block for the construction of complex molecular architectures through cross-coupling reactions. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients. Its unique cyclopropyl structure imparts valuable steric and electronic properties to target molecules.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for the synthesis of drug candidates containing cyclopropane motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the methyl-cyclopropyl group enhances biological activity.
• Material Science Research: Employed in the creation of advanced organic materials, such as organic light-emitting diodes (OLEDs) and liquid crystals.
• Chemical Biology Probes: Acts as a versatile handle for bioconjugation and the development of activity-based probes for target identification.
• Catalyst Ligand Precursor: Can be utilized to synthesize novel ligands for transition metal catalysis.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	1-Methyl-Cyclopropylboronic Acid
CAS No.	1863113-71-6
Molecular Formula	C4H9BO2
Molecular Weight	99.93 g/mol
Synonyms	(1-Methylcyclopropyl)boronic Acid; 1-Methylcyclopropaneboronic Acid; B-(1-Methylcyclopropyl)boronic Acid; 1-Methyl-1-cyclopropylboronic Acid; 1-MCPBA (contextual); Cyclopropylmethylboronic Acid (isomeric); Boronic acid, B-(1-methylcyclopropyl)-
EINECS	Contact for details

Quality Control

Our 1-Methyl-Cyclopropylboronic Acid is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for sensitive applications. Each lot is characterized by modern analytical techniques including NMR, HPLC, and elemental analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.