Description

Rel-(1S,2R)-2-Amino-2-(Thiophen-2-Yl)Cyclohexanol is a high-purity chiral amino alcohol building block of significant interest in advanced organic synthesis. This compound matters as a versatile intermediate for constructing complex molecules with defined stereochemistry, which is critical for developing active pharmaceutical ingredients (APIs) and functional materials. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications in asymmetric catalysis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Catalyst Ligand: Serves as a precursor for synthesizing novel chiral ligands used in transition metal-catalyzed asymmetric reactions, such as hydrogenation and C-C bond formation.
• Agrochemical Synthesis: Used in the development of enantiomerically pure pesticides and herbicides, where specific stereochemistry can influence biological activity and environmental safety.
• Academic & Process Chemistry Research: A valuable building block for methodological studies in organic synthesis and for scaling up synthetic routes to complex targets.
• Material Science Precursor: Potential use in the synthesis of chiral polymers or functionalized surfaces with specific optical or catalytic properties.

Basic Information

Product Name	Rel-(1S,2R)-2-Amino-2-(Thiophen-2-Yl)Cyclohexanol
CAS No.	1860007-18-6
Molecular Formula	C10H15NOS
Molecular Weight	197.30 g/mol
Synonyms	2-Amino-2-(2-thienyl)cyclohexanol; (1S,2R)-2-Amino-2-(thiophen-2-yl)cyclohexan-1-ol; rel-(1S,2R)-2-Amino-2-(2-thienyl)cyclohexanol; 2-(Thiophen-2-yl)-2-aminocyclohexanol; 2-Amino-2-(2-thienyl)-1-cyclohexanol; Amino-thienyl-cyclohexanol; ATC building block
EINECS	Contact for details

Quality Control

Our Rel-(1S,2R)-2-Amino-2-(Thiophen-2-Yl)Cyclohexanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity determination, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.