Description

(2S)-1-Amino-3-(1,2,3,4-Tetrahydroisoquinolin-2-Yl)Propan-2-Ol Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate of significant synthetic value. This compound matters for its role in the development of active pharmaceutical ingredients (APIs) and fine chemicals requiring precise stereochemistry. It is primarily needed by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in advanced organic synthesis and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for central nervous system (CNS) targets.
• Chemical Synthesis Building Block: Used in the construction of complex organic molecules, including alkaloids and other nitrogen-containing heterocycles.
• Asymmetric Catalysis Research: Serves as a ligand precursor or a chiral scaffold in the study and development of new catalytic systems.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Peptidomimetics Research: Utilized in the design and synthesis of peptide analogs and mimetics for biological evaluation.

Basic Information

Product Name	(2S)-1-Amino-3-(1,2,3,4-Tetrahydroisoquinolin-2-Yl)Propan-2-Ol Hydrochloride
CAS No.	1858273-09-2
Molecular Formula	C₁₂H₁₉ClN₂O
Molecular Weight	242.75 g/mol
Synonyms	(2S)-1-Amino-3-(1,2,3,4-tetrahydro-2-isoquinolinyl)-2-propanol hydrochloride; (S)-1-Amino-3-(1,2,3,4-tetrahydroisoquinolin-2-yl)propan-2-ol HCl; 2-Propanol, 1-amino-3-(1,2,3,4-tetrahydro-2-isoquinolinyl)-, (2S)-, hydrochloride; 1858273-09-2; (S)-2-Amino-1-(1,2,3,4-tetrahydroisoquinolin-2-yl)propan-3-ol hydrochloride; Tetrahydroisoquinoline propanolamine derivative HCl
EINECS	Contact for details

Quality Control

Our (2S)-1-Amino-3-(1,2,3,4-Tetrahydroisoquinolin-2-Yl)Propan-2-Ol Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-grade pharmaceutical intermediate standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.