Description

5-Formyl-4-Methyl-1H-Indole-2-Carbonitrile is a high-purity, multi-functional indole derivative serving as a critical building block in advanced organic synthesis. Its unique molecular structure, featuring both formyl and nitrile functional groups, makes it an exceptionally versatile intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex indole-based drug candidates, particularly for oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators with novel modes of action.
• Material Science: Serves as a monomer or functional additive in the creation of advanced polymers, dyes, and photoactive materials.
• Academic & Contract Research: Employed in medicinal chemistry programs and as a standard for analytical method development in academic and CRO laboratories.
• Chemical Synthesis: Utilized in palladium-catalyzed cross-coupling reactions, cyclizations, and other transformations to create diverse chemical libraries.

Basic Information

Product Name	5-Formyl-4-Methyl-1H-Indole-2-Carbonitrile
CAS No.	1857296-22-0
Molecular Formula	C11H8N2O
Molecular Weight	184.20 g/mol
Synonyms	4-Methyl-5-formyl-1H-indole-2-carbonitrile; 1H-Indole-2-carbonitrile, 5-formyl-4-methyl-; 5-Formyl-4-methylindole-2-carbonitrile; 4-Methyl-1H-indole-2-carbonitrile-5-carboxaldehyde; 1857296-22-0; 5-Formyl-4-methyl-1H-indole-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-Formyl-4-Methyl-1H-Indole-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory requirements for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.