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3,6-Dimethoxylpyridazine-4-Boronic Acid Pinacol Ester CAS NO 1855861-18-5
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CAS No.:1855861-18-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3,6-Dimethoxylpyridazine-4-Boronic Acid Pinacol Ester is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its core value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This advanced intermediate is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.
Application
- Pharmaceutical Intermediate: A key synthon for constructing pyridazine-based scaffolds in drug discovery and development programs.
- Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides.
- Material Science Research: Serves as a precursor for creating functional organic materials and liquid crystals.
- Suzuki-Miyaura Cross-Coupling: The primary application is as a boron-containing coupling partner for forming carbon-carbon bonds with aryl/vinyl halides.
- Chemical Library Development: Enables the rapid, parallel synthesis of diverse compound libraries for high-throughput screening.
- Process Chemistry: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
Basic Information
| Product Name | 3,6-Dimethoxylpyridazine-4-Boronic Acid Pinacol Ester |
| CAS No. | 1855861-18-5 |
| Molecular Formula | C13H19BN2O4 |
| Molecular Weight | 278.11 g/mol |
| Synonyms | 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3,6-dimethoxypyridazine; 3,6-Dimethoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridazine; 3,6-Dimethoxypyridazine-4-boronic acid pinacol ester; 4-Boronic acid, 3,6-dimethoxypyridazine-, pinacol ester; 3,6-Dimethoxy-4-pyridazineboronic acid pinacol ester |
| EINECS | Contact for details |
Quality Control
Our 3,6-Dimethoxylpyridazine-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee batch-to-batch consistency and support your regulatory documentation needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (HPLC) | Conforms |
| Identification (NMR) | Conforms |
| Purity (HPLC) | ≥97.0% |
| Water Content (KF) | ≤0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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