Description

4-Fluoroisoquinolin-8-Amine is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, particularly those targeting specific biological pathways. It is primarily needed by research institutions and industrial R&D departments focused on medicinal chemistry, where its unique fluorinated isoquinoline scaffold is utilized to modulate the potency, selectivity, and metabolic stability of candidate molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) for potential therapeutic agents.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to develop new drug candidates.
• Agrochemical Development: Serves as a building block for creating novel pesticides and herbicides with enhanced efficacy.
• Chemical Biology Probes: Employed in the design of molecular probes for studying enzyme function and biological pathways.
• Material Science: Potential monomer or precursor for the synthesis of specialty polymers and advanced organic materials.

Basic Information

Product Name	4-Fluoroisoquinolin-8-Amine
CAS No.	1841081-81-9
Molecular Formula	C9H7FN2
Molecular Weight	162.16 g/mol
Synonyms	8-Amino-4-fluoroisoquinoline; 4-Fluoro-8-aminoisoquinoline; 4-Fluoro-8-isoquinolinamine; 4-Fluoroisoquinolin-8-ylamine; 1841081-81-9; 4-Fluoro-8-isoquinolamine; 8-Isoquinolinamine, 4-fluoro-
EINECS	Contact for details

Quality Control

Our 4-Fluoroisoquinolin-8-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP standards for advanced intermediates used in research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.