Description

5-Bromo-4-Fluoroisoquinoline is a high-value halogenated isoquinoline derivative, a crucial building block in modern synthetic organic chemistry. Its core value lies in its dual functionalization, providing versatile reactivity for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs). This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors seeking to innovate and scale novel compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of potential drug candidates, especially in kinase inhibitor research and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging the biological activity of the fluorinated isoquinoline scaffold.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Chemical Synthesis: Acts as a versatile building block for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to introduce complex substituents.
• Life Science Reagents: Utilized in the design and synthesis of fluorescent probes, biomarkers, and other biochemical tools.

Basic Information

Product Name	5-Bromo-4-Fluoroisoquinoline
CAS No.	1841081-73-9
Molecular Formula	C9H5BrFN
Molecular Weight	226.05 g/mol
Synonyms	4-Fluoro-5-bromoisoquinoline; 5-Bromo-4-fluoro-isoquinoline; Isoquinoline, 5-bromo-4-fluoro-; 1841081-73-9
EINECS	Contact for details

Quality Control

Our 5-Bromo-4-Fluoroisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.