Description

3-Chloro-6-Fluoro-Isoquinolin-5-Ylamine is a high-purity, halogenated isoquinoline derivative serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular scaffold, which is essential for constructing complex pharmacophores and functional materials. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive heterocyclic structure.
• Material Science: Serves as a monomer or functional additive in the creation of advanced polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or linker in bioconjugation and the study of biological pathways.
• Academic & Contract Research: Utilized in universities and CROs for methodological development and exploratory chemistry projects.

Basic Information

Product Name	3-Chloro-6-Fluoro-Isoquinolin-5-Ylamine
CAS No.	1841079-95-5
Molecular Formula	C9H6ClFN2
Molecular Weight	196.61 g/mol
Synonyms	5-Amino-3-chloro-6-fluoroisoquinoline; 3-Chloro-6-fluoro-5-isoquinolinamine; 3-Chloro-6-fluoro-5-aminoisoquinoline; 3-Chloro-6-fluoroisoquinolin-5-amine; 1841079-95-5; 5-Isoquinolinamine, 3-chloro-6-fluoro-; 3-Chloro-6-fluoro-5-isoquinolylamine
EINECS	Contact for details

Quality Control

Our 3-Chloro-6-Fluoro-Isoquinolin-5-Ylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere if possible and opened only in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.