Description

n-[(1S,2R,3E)-2-Hydroxy-1-(Hydroxymethyl)-3-Heptadecen-1-Yl-D7]-Tetracosanamide is a high-purity, deuterated ceramide analog, a critical class of bioactive lipids essential for cellular membrane structure and signaling. This compound is specifically engineered for advanced research and development, offering superior isotopic purity for precise metabolic and pharmacokinetic studies. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and specialty chemical manufacturers focused on dermatology, oncology, and lipid metabolism.

Application

• Biomedical Research: As a deuterium-labeled internal standard for the accurate quantification of natural ceramides in biological matrices via LC-MS/MS.
• Drug Discovery & Development: For tracing metabolic pathways, studying drug-lipid interactions, and investigating the role of ceramides in apoptosis and cell signaling.
• Cosmeceutical R&D: In the formulation and testing of high-end skincare products aimed at skin barrier repair and anti-aging, where ceramide analogs are key active ingredients.
• Diagnostic Assay Development: Used in the calibration and validation of diagnostic kits targeting sphingolipid disorders.
• Chemical Synthesis: Serves as a sophisticated building block for the synthesis of novel, labeled sphingolipid derivatives.

Basic Information

Product Name	n-[(1S,2R,3E)-2-Hydroxy-1-(Hydroxymethyl)-3-Heptadecen-1-Yl-D7]-Tetracosanamide
CAS No.	1840942-15-5
Molecular Formula	C41H74D7NO3
Molecular Weight	~ 647.2 g/mol
Synonyms	Ceramide (d7) Analog; Tetracosanamide, N-[(1S,2R,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl-d7]-; Deuterated Ceramide; N-[(1S,2R,3E)-2-Hydroxy-1-(Hydroxymethyl)-3-Heptadecen-1-yl-d7]tetracosanamide; Labeled Sphingolipid; C24 Ceramide-d7; Isotopically Labeled Ceramide; Bioactive Lipid Standard.
EINECS	Contact for details

Quality Control

Every batch of our deuterated ceramide is manufactured under strict quality systems and undergoes comprehensive analytical characterization to ensure identity, purity, and isotopic enrichment. We provide full traceability and Certificates of Analysis (COA) detailing results from NMR, HPLC, and mass spectrometry. Our quality commitment aligns with the stringent requirements for research-grade biochemicals, supporting GLP and ISO standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuterium, MS)	≥ 98 atom % D
Chemical Purity (Titration)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.